HCA-guided Low homology modelling

HCA-guided low homology modeling

This webpage contains supplementary material to
Pedro J. Silva (2007) Assessing the reliability of sequence similarities detected through hydrophobic cluster analysis Proteins: Structure, Function and Bioinformatics, 70, 1588-1594.

Comparison of models generated through this method with the best CASP models and experimentally-derived structures.


T0315

Template used: 1J6O Chain A       Identity 38 % Best CASP model
Aligned length= 248, RMSD= 1.35, TM-score=0.95638 Aligned length= 248, RMSD= 0.88, TM-score=0.97905

T0313

Template used: 1CZ7 Chain D       Identity 42 % Best CASP model
Aligned length= 308, RMSD= 2.53, TM-score=0.89831 Aligned length= 315, RMSD= 2.34, TM-score=0.92150

T0308

Template used: 1KSJ Chain A       Identity 36 % Best CASP model
Aligned length= 164, RMSD= 1.63, TM-score=0.92318 Aligned length= 164, RMSD= 1.41, TM-score=0.94383

T0305

Template used: 1JLN Chain A       Identity 33 % Best CASP model
Aligned length= 267, RMSD= 2.07, TM-score=0.89293 Aligned length= 276, RMSD= 1.08, TM-score=0.97065

T0302

Template used: 1AGR       Identity 53 % Best CASP model
Aligned length= 121, RMSD= 1.98, TM-score=0.79129 Aligned length= 132, RMSD= 1.58, TM-score=0.88517

T0292

Template used: 1F3M Chain D       Identity 26 % Best CASP model
Aligned length= 231, RMSD= 3.15, TM-score=0.76446 Aligned length= 244, RMSD= 2.47, TM-score=0.88493

T0268

Template used: 1M6Y       Identity 47 % Best CASP model
Aligned length= 281, RMSD= 1.75, TM-score=0.93556 Aligned length= 281, RMSD= 1.67, TM-score=0.94699

T0269

Template used: 1QQ2       Identity 35 % Best CASP model
Aligned length= 161, RMSD= 2.26, TM-score=0.61781 Aligned length= 228, RMSD= 2.73, TM-score=0.84662

T0233

Template used: 1KGZ       Identity 37% Best CASP model
Aligned length= 326, RMSD= 2.18, TM-score=0.90714 Aligned length= 331, RMSD= 1.72, TM-score=0.95014

T0246

Template used: 9ICD       Identity 25 % Best CASP model
Aligned length= 326, RMSD= 2.78, TM-score=0.81752 Aligned length= 353, RMSD= 1.28, TM-score=0.94591