HCA-guided low homology modeling

HCA-guided Low homology modelling

This webpage contains supplementary material to
Pedro J. Silva (2007) "Assessing the reliability of sequence similarities detected through hydrophobic sequence analysis" Proteins: Structure, Function and Bioinformatics, 70, 1588-1594.

Comparison of models generated through this method with experimentally-derived structures.




1MYT

Template used: 1A0X chain D       Identity 24% Aligned length= 139, RMSD= 1.81, TM-score=0.84823

1IT3

Template used: 1DM1       Identity 19% Aligned length= 132, RMSD= 2.21, TM-score=0.76726

1EKM

Template used: 1QAF       Identity 25% Aligned length= 622, RMSD= 2.74, TM-score=0.88896

1CPR chain S

Template used: 1BBH       Identity 23% Aligned length= 126, RMSD= 1.62, TM-score=0.88669

1A22

Template used: 1N9D       Identity 22% Aligned length= 157, RMSD= 3.78, TM-score=0.63064

1B8A

Template used: 1C0A       Identity 27%       Aligned length= 372, RMSD= 3.68, TM-score=0.73273